356 Meal feeding compared with continuous feeding enhances insulin and amino acid signaling to translation initiation in skeletal muscle of pigs
نویسندگان
چکیده
منابع مشابه
Regulation of translation initiation by insulin and amino acids in skeletal muscle of neonatal pigs.
Previous studies have shown that intravenous infusion of insulin and/or amino acids reproduces the feeding-induced stimulation of muscle protein synthesis in neonates and that insulin and amino acids act independently to produce this effect. The goal of the present study was to delineate the regulatory roles of insulin and amino acids on muscle protein synthesis in neonates by examining transla...
متن کاملAnabolic Signaling and Protein Deposition Are Enhanced by Intermittent as Compared 1 with Continuous Feeding in Skeletal Muscle of Neonates 2 Running title : Intermittent feeding increases muscle protein
20 Orogastric tube feeding is indicated for neonates with impaired ability to ingest, and can 21 be administered by intermittent bolus or continuous schedule. Our aim was to determine 22 whether feeding modalities affect muscle protein deposition and to identify mechanisms 23 involved. Neonatal pigs were overnight fasted (FAS) or fed the same amount of food 24 continuously (CON) or intermittent...
متن کاملAnabolic signaling and protein deposition are enhanced by intermittent compared with continuous feeding in skeletal muscle of neonates.
Orogastric tube feeding is indicated for neonates with impaired ability to ingest and can be administered by intermittent bolus or continuous schedule. Our aim was to determine whether feeding modalities affect muscle protein deposition and to identify mechanisms involved. Neonatal pigs were overnight fasted (FAS) or fed the same amount of food continuously (CON) or intermittently (INT; 7 × 4 h...
متن کاملDevelopmental changes in the feeding-induced stimulation of translation initiation in muscle of neonatal pigs.
The rapid gain in skeletal muscle mass in the neonate is associated with a marked elevation in skeletal muscle protein synthesis in response to feeding. The feeding-induced response decreases with development. To determine whether the response to feeding is regulated at the level of translation initiation, the expression, phosphorylation, and function of a number of eukaryotic initiation factor...
متن کاملActivation by insulin and amino acids of signaling components leading to translation initiation in skeletal muscle of neonatal pigs is developmentally regulated.
Insulin and amino acids act independently to stimulate protein synthesis in skeletal muscle of neonatal pigs, and the responses decrease with development. The purpose of this study was to compare the separate effects of fed levels of INS and AA on the activation of signaling components leading to translation initiation and how these responses change with development. Overnight-fasted 6- (n = 4/...
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ژورنال
عنوان ژورنال: Journal of Animal Science
سال: 2019
ISSN: 0021-8812,1525-3163
DOI: 10.1093/jas/skz258.261